Giant Buschke-Löwenstein tumor: Case report of a patient with no history of immune system compromise

1,
María Rojas Pérez2,
María Isabel Correa Polo1
1. Departamento de Ginecología y Obstetricia, Hospital Santo Tomás, Ciudad de Panamá, Panamá; 2. Departamento de Ginecología y Obstetricia, Caja de Seguro Social, Ciudad de Panamá, Panamá;

Authors

DOI:

https://doi.org/10.37980/im.journal.revcog.es.20262720

Keywords:

condyloma acuminatum, female genital tract neoplasms, human papillomavirus, vulva, verrucous carcinoma

Abstract

Buschke–Löwenstein tumor is a rare variant of condyloma acuminatum, characterized by exophytic growth and locally invasive behavior, but with low metastatic potential. It is mainly associated with human papillomavirus genotypes 6 and 11, although it may coexist with high-risk types. We report the case of a 43-year-old woman with a 17-year history of a progressively enlarging vulvar mass, ulcerated, malodorous, and with intermittent bleeding. The patient was clinically evaluated and diagnosed with Buschke–Löwenstein tumor and was referred to a national reference center for specialized surgical management. Treatment is based on wide surgical excision with clear margins due to its high recurrence rate and potential for malignant transformation. Early identification and timely intervention are essential to reduce complications and improve prognosis.

Published

2026-04-30

Issue

Section

Casos Clínicos